Dapsone topical and Sodium Nitroprusside
Determining the interaction of Dapsone topical and Sodium Nitroprusside and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using sodium nitroprusside together with dapsone topical. Sodium nitroprusside can cause a condition called methemoglobinemia that reduces the oxygen-carrying capacity of the blood to different organs, and combining the medication with dapsone topical may increase the risk. Infants and patients with certain conditions such as glucose-6-phosphate dehydrogenase deficiency or anemia are more likely to develop this condition. You should seek immediate medical attention if you notice signs and symptoms such as a gray discoloration of the skin, mouth, or nail bed; nausea; headache; dizziness; lightheadedness; fatigue; shortness of breath; rapid or shallow breathing; a rapid heartbeat; anxiety; and confusion. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of oral or topical dapsone with other agents associated with methemoglobinemia may have additive effects and theoretically increase the risk of drug-induced methemoglobinemia. Oral and topical dapsone have been associated with methemoglobinemia, and the risk is increased in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency or congenital or idiopathic methemoglobinemia.
MANAGEMENT: Concurrent use of oral or topical dapsone with other methemoglobinemia-inducing medications should be followed with monitoring for signs and symptoms of methemoglobinemia (e.g., cyanosis, hypoxia).
- "Product Information. Aczone (dapsone topical)." QLT USA, Inc, Fort Collins, CO.
- Cerner Multum, Inc. "Australian Product Information." O 0
Generic Name: dapsone topical
Brand name: Aczone
Synonyms: Dapsone (Topical)
Generic Name: nitroprusside
Brand name: Nitropress, Nipride RTU
Synonyms: Nitroprusside
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Dapsone topical-Sodium Nitroprusside Injection
- Dapsone topical-Sodium nitroprusside Intravenous
- Dapsone topical-Sodium oxybate
- Dapsone topical-Sodium phenylacetate and benzoate Intravenous
- Dapsone topical-Sodium Phenylacetate and Sodium Benzoate
- Dapsone topical-Sodium Phenylacetate and Sodium Benzoate Injection
- Sodium Nitroprusside-Daptacel
- Sodium Nitroprusside-Daptomycin
- Sodium Nitroprusside-Daptomycin Injection
- Sodium Nitroprusside-Daptomycin Intravenous
- Sodium Nitroprusside-Daranide
- Sodium Nitroprusside-Daraprim