Daraprim and Lomitapide Mesylate

• Generic Name: pyrimethamine
• Dosage Forms: tablet
• Other Brand Names: Daraprim

Daraprim is an antiparasite medicine that helps prevent parasites from growing and reproducing in the body.

Daraprim is used in adults and children to treat or prevent certain types of malaria. However, this medicine is generally not preferred as a medicine to prevent malaria while traveling. When used to treat malaria, this medicine should be used together with a faster-acting anti-malaria medicine such as chloroquine or quinine.

Daraprim is also used to treat toxoplasmosis, an infection caused by the Toxoplasma parasite.

Daraprim may also be used for purposes not listed in this medication guide.

• Generic Name: lomitapide
• Dosage Forms: n.a.
• Other Brand Names: Juxtapid

Adjunct to a low-fat diet and other lipid-lowering treatments, including LDL apheresis where available, to reduce LDL-cholesterol, total cholesterol, apolipoprotein B (apo B), and non-HDL-cholesterol concentrations in the management of homozygous familial hypercholesterolemia (designated an orphan drug by US FDA for use in this condition).

Safety and efficacy not established in patients with hypercholesterolemia who do not have homozygous familial hypercholesterolemia.

Effects on cardiovascular morbidity and mortality not established.