Daratumumab Intravenous and Encorafenib

• Generic Name: daratumumab
• Dosage Forms: n.a.
• Other Brand Names: Darzalex

Daratumumab injection is used alone or together with other medicines to treat multiple myeloma (a type of bone marrow cancer). It is used alone in patients who have received at least 3 prior treatments that did not work well, including a proteasome inhibitor and an immunomodulatory agent, or who did not respond to both a proteasome inhibitor and an immunomodulatory agent.

Daratumumab injection is also used in combination with lenalidomide and dexamethasone, or bortezomib and dexamethasone, to treat patients with multiple myeloma who have received at least 1 previous treatment.

Daratumumab injection is also used together with bortezomib, melphalan, and prednisone to treat patients with newly diagnosed multiple myeloma who cannot receive autologous stem cell transplant.

Daratumumab injection is also used in combination with pomalidomide and dexamethasone to treat patients with multiple myeloma who have received at least two treatments (including lenalidomide and a proteasome inhibitor).

Daratumumab is to be given only by or under the supervision of your doctor.

• Generic Name: encorafenib
• Dosage Forms: n.a.
• Other Brand Names: Braftovi

Encorafenib is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Encorafenib is used in combination with another medicine called binimetinib (Mektovi) to treat melanoma (skin cancer) in people who have a "BRAF" gene mutation. These medicines are for use in treating melanoma that cannot be treated with surgery or has spread to other parts of the body.

Encorafenib may also be used for purposes not listed in this medication guide.