Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Fumarate and Ziconotide Intrathecal

• Generic Name: cobicistat / darunavir / emtricitabine / tenofovir alafenamide
• Dosage Forms: n.a.
• Other Brand Names: Symtuza

Darunavir, cobicistat, emtricitabine, and tenofovir alafenamide fumarate is a four-drug combination of darunavir (DRV), an HIV-1 protease inhibitor, cobicistat (COBI), a CYP3A inhibitor, and emtricitabine (FTC) and tenofovir alafenamide (TAF), both HIV-1 NRTIs, and is indicated as a complete regimen for the treatment of HIV-1 infection in adults who have no prior antiretroviral treatment history or who are virologically suppressed (HIV-1 RNA less than 50 copies per mL) on a stable antiretroviral regimen for at least 6 months and have no known substitutions associated with resistance to darunavir or tenofovir.

• Generic Name: ziconotide
• Dosage Forms: n.a.
• Other Brand Names: Prialt

Ziconotide injection is used to relieve severe chronic pain in patients who have already been treated with other medicines (e.g., morphine) and did not work well.

Ziconotide is to be given only by or under the direct supervision of a doctor.