Darunavir Tablets and Epidiolex Oral Solution
Determining the interaction of Darunavir Tablets and Epidiolex Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Darunavir may increase the blood levels of cannabidiol. This may increase side effects such as drowsiness, diarrhea, decreased appetite, and liver problems. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSE: Coadministration with moderate or potent inhibitors of CYP450 2C19 and/or CYP450 3A4 may increase the plasma concentrations of cannabidiol, which is primarily metabolized by these isoenzymes in the liver and gut.
MANAGEMENT: Dosage reduction of cannabidiol should be considered when coadministered with moderate or potent inhibitors of CYP450 2C19 and/or CYP450 3A4.
- "Product Information. Epidiolex (cannabidiol)." Greenwich Biosciences Inc, Carlsbad, CA.
Generic Name: darunavir
Brand name: Prezista
Synonyms: Darunavir
Generic Name: cannabidiol
Brand name: Epidiolex
Synonyms: Epidiolex
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Darunavir Tablets-Epiduo
- Darunavir Tablets-Epiduo Forte
- Darunavir Tablets-Epifoam
- Darunavir Tablets-Epiject Iv
- Darunavir Tablets-Epiklor
- Darunavir Tablets-Epinal
- Epidiolex Oral Solution-Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide
- Epidiolex Oral Solution-Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Fumarate
- Epidiolex Oral Solution-Darvocet
- Epidiolex Oral Solution-Darvocet A500
- Epidiolex Oral Solution-Darvocet-N
- Epidiolex Oral Solution-Darvon