De-Sone LA injection and Elvitegravir
Determining the interaction of De-Sone LA injection and Elvitegravir and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Dexamethasone may decrease the blood levels of elvitegravir, which may reduce its effectiveness in treating HIV infection. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Coadministration with inducers of CYP450 3A4 isoenzymes may reduce the plasma concentrations of elvitegravir, which is primarily metabolized by the isoenzyme.
MANAGEMENT: Given the risk of reduced viral susceptibility and resistance development associated with subtherapeutic antiretroviral drug levels, the manufacturers of elvitegravir single-ingredient and combination products recommend avoiding concomitant use. Alternative treatment combinations that do not include metabolic inducers should be considered whenever possible.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Vitekta (elvitegravir)." Gilead Sciences, Foster City, CA.
- Cerner Multum, Inc. "Australian Product Information." O 0
Generic Name: dexamethasone
Brand name: De-Sone LA, Dexacen-4, Dexasone, Dexasone LA, Solurex, Solurex LA, Baycadron, Dexamethasone Intensol, DexPak 10 Day Taperpak, DexPak 13 DayTaperpak, DexPak 6 DayTaperpak, Decadron, DexPak, TaperDex, Zema-Pak, ZoDex, Zonacort
Synonyms: De-Sone LA (injection)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- De-Sone LA injection-Elvitegravir, cobicistat, emtricitabine, and tenofovir
- De-Sone LA injection-Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide
- De-Sone LA injection-Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate
- De-Sone LA injection-Elzonris
- De-Sone LA injection-Emapalumab
- De-Sone LA injection-Emapalumab-lzsg
- Elvitegravir-Deblitane
- Elvitegravir-Decadron
- Elvitegravir-Decadron Elixir
- Elvitegravir-Decara
- Elvitegravir-Decavac
- Elvitegravir-Decavac (Td) Td
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir 
De-Sone LA injection - Elvitegravir