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De-Sone LA injection and Tecfidera

Determining the interaction of De-Sone LA injection and Tecfidera and the possibility of their joint administration.

Check result:
De-Sone LA injection <> Tecfidera
Relevance: 11.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.GENERALLY AVOID: The use of diroximel fumarate or dimethyl fumarate with other immunosuppressive or myelosuppressive agents may increase the risk of infections. Both diroximel fumarate and dimethyl fumarate alone may cause lymphopenia and serious infections, and the risk may theoretically be increased due to additive immune system effects in the presence of other myelo- or immunosuppressive therapies. MANAGEMENT: The safety and efficacy of diroximel fumarate or dimethyl fumarate in combination with other immunosuppressive agents have not been evaluated. Until further information is available, the use of diroximel fumarate or dimethyl fumarate with other immunosuppressive or myelosuppressive agents should be avoided. References "Product Information. Vumerity (diroximel fumarate)." Alkermes, Inc, Cambridge, MA.

Professional:

GENERALLY AVOID: The use of diroximel fumarate or dimethyl fumarate with other immunosuppressive or myelosuppressive agents may increase the risk of infections. Both diroximel fumarate and dimethyl fumarate alone may cause lymphopenia and serious infections, and the risk may theoretically be increased due to additive immune system effects in the presence of other myelo- or immunosuppressive therapies.

MANAGEMENT: The safety and efficacy of diroximel fumarate or dimethyl fumarate in combination with other immunosuppressive agents have not been evaluated. Until further information is available, the use of diroximel fumarate or dimethyl fumarate with other immunosuppressive or myelosuppressive agents should be avoided.

References
  • "Product Information. Vumerity (diroximel fumarate)." Alkermes, Inc, Cambridge, MA.
De-Sone LA injection

Generic Name: dexamethasone

Brand name: De-Sone LA, Dexacen-4, Dexasone, Dexasone LA, Solurex, Solurex LA, Baycadron, Dexamethasone Intensol, DexPak 10 Day Taperpak, DexPak 13 DayTaperpak, DexPak 6 DayTaperpak, Decadron, DexPak, TaperDex, Zema-Pak, ZoDex, Zonacort

Synonyms: De-Sone LA (injection)

Tecfidera

Generic Name: dimethyl fumarate

Brand name: Tecfidera, Tecfidera Starter Pack

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction