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Declomycin and Pitressin Injection

Determining the interaction of Declomycin and Pitressin Injection and the possibility of their joint administration.

Check result:
Declomycin <> Pitressin Injection
Relevance: 10.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Talk to your doctor before using demeclocycline together with vasopressin. Combining these medications may reduce the effects of vasopressin. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Demeclocycline may antagonize the antidiuretic effects of vasopressin. The mechanism is not completely understood, but demeclocycline is thought to block the binding of antidiuretic hormone to its receptor.

MANAGEMENT: Coadministration of demeclocycline and vasopressin should generally be avoided due to antagonistic effects on the kidney.

References
  • "Product Information. Pitressin (vasopressin)." Parke-Davis, Morris Plains, NJ.
Declomycin

Generic Name: demeclocycline

Brand name: Declomycin

Synonyms: n.a.

Pitressin Injection

Generic Name: vasopressin

Brand name: Pitressin Synthetic, Vasostrict, Pitressin

Synonyms: Pitressin Synthetic

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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