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Decorel Forte Plus Cold/Cough and Inversine

Determining the interaction of Decorel Forte Plus Cold/Cough and Inversine and the possibility of their joint administration.

Check result:
Decorel Forte Plus Cold/Cough <> Inversine
Relevance: 10.10.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using phenylephrine together with mecamylamine may cause an increase in blood pressure. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Limited data suggest that methyldopa and other sympatholytics may increase or prolong the pressor effect of sympathomimetics. Hypertension may result. Data exist for phenylpropanolamine and norepinephrine.

MANAGEMENT: If these drugs must be coadministered, blood pressure should be closely monitored. Discontinuation of the sympathomimetic may be necessary if hypertension develops.

References
  • McLaren EH "Severe hypertension produced by interaction of phenylpropanolamine with methyldopa and oxprenolol." Br Med J 2 (1976): 283-4
  • "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
Decorel Forte Plus Cold/Cough

Generic Name: acetaminophen / dextromethorphan / guaifenesin / phenylephrine

Brand name: Decorel Forte Plus Cold/Cough, Mucinex Fast-Max, Mucinex Fast-Max Cold and Flu, Mucinex Fast-Max Congestion and Cold, Mucinex Fast-Max Severe Cold, Tylenol Cold Multi-Symptom Severe Daytime, Tylenol Cold Head Congestion Severe, Non-Pseudo Cold Relief, Phenflu DM, Sudafed PE Cold & Cough, Cold & Cough PE, Cold Head Congestion Severe Daytime, Cold Multi-Symptom Severe Daytime Cool Ice, Tylenol Cold & Flu Severe, Mucinex Children's Multi-Symptom Cold & Fever, Mucinex Fast-Max Cold, Flu & Sore Throat, Mucinex Fast-Max Severe Congestion & Cold, Cough & Sore Throat, DayQuil Severe Cold & Flu, Adult Cold, Cold & Flu Severe, Mucinex Sinus-Max Severe Congestion Relief, Delsym Cough + Cold Daytime, Severe Day Time Cold & Flu, Mucinex Fast-Max Cold & Flu, Mucinex Sinus-Max Pressure, Pain & Cough

Synonyms: n.a.

Inversine

Generic Name: mecamylamine

Brand name: Inversine, Vecamyl

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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