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Deferasirox and Mintox Plus

Determining the interaction of Deferasirox and Mintox Plus and the possibility of their joint administration.

Check result:
Deferasirox <> Mintox Plus
Relevance: 26.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Talk to your doctor before using deferasirox together with aluminum hydroxide. Products that contain aluminum may interfere with the absorption of deferasirox and reduce its effectiveness. If possible, you should avoid taking aluminum hydroxide or other aluminum-containing products while your are being treated with deferasirox. Your doctor may be able to suggest safer alternatives to aluminum hydroxide that do not interact with deferasirox. Otherwise, you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition worsens. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Although deferasirox has a lower affinity for aluminum than for iron, it can theoretically bind aluminum in the gastrointestinal tract.

MANAGEMENT: Deferasirox should not be taken with aluminum-containing preparations.

References
  • "Product Information. Exjade (deferasirox)." Novartis Pharmaceuticals, East Hanover, NJ.
Deferasirox

Generic Name: deferasirox

Brand name: Exjade, Jadenu, Jadenu Sprinkle

Synonyms: n.a.

Mintox Plus

Generic Name: aluminum hydroxide / magnesium hydroxide / simethicone

Brand name: Gelusil, Mintox Plus, Almacone, Mag-al Plus, Mi-Acid, Milantex, Mintox, Mylanta Maximum Strength, Rulox, Mylanta Fast Acting, Mylanta DS Fast Acting, Maalox Plus, Masanti DS, Masanti II, Masanti, Alamag Plus, Mi-Acid II, Almacone-2, Mylagen, Mylagen-II, Magaant, Ri-Mox Plus, Rulox Plus, Di-Gel, Ri-Gel II, Uni-Lan, Uni-Lan II, Urban, Urban DS, Maldroxal Plus, Maalox Plus Extra Strength, Tempo, Mylanta, Maalox Max, Maalox, Aldroxicon I, Aldroxicon II, Maalox Antacid Antigas Regular Strength, Mintox Extra Strength, Mintox Maximum Strength, Comfort Gel Original, Comfort Gel Extra Strength, Mylanta Maximum Strength Cherry, Maalox Max Wild Berry, Maalox Advanced Maximum Strength, Milantex Maximum Strength, Maalox Advanced Regular Strength, Geri-Lanta, Mag-al Plus XS, Mylanta Maximum Strength Vanilla Caramel, Mi-Acid Maximum Strength, Di-Gel Liquid

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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Disease interaction