Deferasirox Tablets and Triaminic Softchew Throat Pain and Cough
Determining the interaction of Deferasirox Tablets and Triaminic Softchew Throat Pain and Cough and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Deferasirox may increase the blood levels and effects of acetaminophen. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with deferasirox may increase the plasma concentrations of drugs that are substrates of the CYP450 1A2 isoenzyme. The mechanism is decreased clearance due to inhibition of CYP450 1A2 activity by deferasirox. In a study of healthy volunteers, administration of the CYP450 1A2 substrate theophylline (120 mg single dose) in combination with deferasirox (repeated dosing of 30 mg/kg/day) resulted in an approximate doubling of theophylline systemic exposure (AUC) and elimination half-life.
MANAGEMENT: Caution is advised if deferasirox must be used concurrently with medications that undergo metabolism by CYP450 1A2, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever deferasirox is added to or withdrawn from therapy.
- "Product Information. Exjade (deferasirox)." Novartis Pharmaceuticals, East Hanover, NJ.
Generic Name: deferasirox
Brand name: Exjade, Jadenu, Jadenu Sprinkle
Synonyms: Deferasirox
Generic Name: acetaminophen / dextromethorphan / pseudoephedrine
Brand name: Alka-Seltzer Plus Flu Liquigels, Comtrex Non-Drowsy, Dayquil Liquicaps, Daytime Cold, Non-Drowsy Daytime, Robitussin Honey Flu Non-Drowsy, Theraflu Daytime Severe Cold, Theraflu Severe Cold & Congestion Non-Drowsy, Triaminic Cough & Sore Throat, Triaminic Softchew Throat Pain and Cough, Triaminic Softchews Cough & Sore Throat, EQL Severe Cold, GNP Day Time D Cold/Flu, PX Daytime Multi-Symptom, RA Acetaminophen Flu Cold
Synonyms: Acetaminophen, dextromethorphan, and pseudoephedrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Deferasirox Tablets-Triaminic Softchews Allergy Congestion
- Deferasirox Tablets-Triaminic Softchews Allergy Sinus
- Deferasirox Tablets-Triaminic Softchews Chest Congestion
- Deferasirox Tablets-Triaminic Softchews Cough & Sore Throat (pseudoephedrine)
- Deferasirox Tablets-Triamterene
- Deferasirox Tablets-Triamterene and hydrochlorothiazide
- Triaminic Softchew Throat Pain and Cough-Deferasirox Tablets For Oral Suspension
- Triaminic Softchew Throat Pain and Cough-Deferiprone
- Triaminic Softchew Throat Pain and Cough-Deferiprone Oral Solution
- Triaminic Softchew Throat Pain and Cough-Deferiprone Tablets
- Triaminic Softchew Throat Pain and Cough-Deferoxamine
- Triaminic Softchew Throat Pain and Cough-Deferoxamine Injection