Deferoxamine and Vitamin C
Determining the interaction of Deferoxamine and Vitamin C and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using ascorbic acid together with deferoxamine can cause heart problems and cataracts. Ascorbic acid should not be started until after the first month of deferoxamine treatment. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSE: Although ascorbic acid is commonly given during deferoxamine treatment, cardiac disorders (left ventricular dysfunction) and cataracts have been reported with high doses (more than 200 mg/day) or long-term use. Higher doses of vitamin C do not provide any additional benefit. The mechanism is unknown.
MANAGEMENT: Ascorbic acid should not be initiated until after the first month of treatment with deferoxamine. Doses should be given on the same days that deferoxamine is administered. Doses should not exceed 200 mg per day (in divided doses) for adults, 50 mg per day for children younger than 10 years, and 100 mg per day for children over 10 years. Cardiac function should be monitored during concomitant use.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Multum Information Services, Inc. Expert Review Panel"
Generic Name: ascorbic acid
Brand name: Acerola, Ascorbic Acid Quick Melts, C/Rose Hips, Cecon, Cemill 500, C-Time, Ester-C, N Ice with Vitamin C, Sunkist Vitamin C, Vasoflex HD, Vicks Vitamin C Drops, Vitamin C, Cenolate, Mega-C-Acid Plus, Cee-500, C-500-Gr, Centrum Singles-Vitamin C, Ascot, Cevi-Bid, Vitamin C TR, Vitamin C with Rose Hips, Cemill 1000, Ascor L NC, Ascor, Ascor L 500, Betac, Cemill, Protexin
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Deferoxamine-Vitamin C Powder
- Deferoxamine-Vitamin D
- Deferoxamine-Vitamin D Ergocalciferol
- Deferoxamine-Vitamin D2
- Deferoxamine-Vitamin D3
- Deferoxamine-Vitamin Deficiency System
- Vitamin C-Deferoxamine Injection
- Vitamin C-Deferoxamine Mesylate
- Vitamin C-Defibrotide
- Vitamin C-Defibrotide Intravenous
- Vitamin C-Defibrotide Sodium
- Vitamin C-Definity
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C 
Deferoxamine - Vitamin C