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Deferoxamine Injection and Prochlorperazine

Determining the interaction of Deferoxamine Injection and Prochlorperazine and the possibility of their joint administration.

Check result:
Deferoxamine Injection <> Prochlorperazine
Relevance: 12.01.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using prochlorperazine together with deferoxamine. Using these medications together may result in a condition known as metabolic encephalopathy. This has been reported in two patients who developed loss of consciousness for 48 to 72 hours. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Limited data suggest that the concomitant administration of deferoxamine and prochlorperazine may result in transient metabolic encephalopathy. Loss of consciousness for 48 to 72 hours has been reported in 2 patients. The mechanism is unknown.

MANAGEMENT: The manufacturer recommends that concomitant use should be avoided.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Product Information. Desferal (deferoxamine)." Novartis Pharmaceuticals, East Hanover, NJ.
Deferoxamine Injection

Generic Name: deferoxamine

Brand name: Desferal

Synonyms: Deferoxamine

Prochlorperazine

Generic Name: prochlorperazine

Brand name: Compazine, Compro

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle