Defibrotide Sodium and Diuril Injection

• Generic Name: defibrotide
• Dosage Forms: n.a.
• Other Brand Names: Defitelio

Treatment of hepatic VOD, also known as sinusoidal obstruction syndrome (SOS), with renal or pulmonary dysfunction following hematopoietic stem cell transplantation (HSCT). Designated orphan drug by FDA for treatment of hepatic VOD.

Improves day-100 post-HSCT survival rates compared with historical controls receiving supportive or other therapies.

• Generic Name: chlorothiazide
• Dosage Forms: injection
• Other Brand Names: Diuril, Diuril Sodium

Chlorothiazide is a diuretic (water pill) that is used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen.

Chlorothiazide is also used to treat high blood pressure (hypertension).

Chlorothiazide may also be used for purposes not listed in this medication guide.