Defibrotide Sodium and Toremifene

• Generic Name: defibrotide
• Dosage Forms: n.a.
• Other Brand Names: Defitelio

Treatment of hepatic VOD, also known as sinusoidal obstruction syndrome (SOS), with renal or pulmonary dysfunction following hematopoietic stem cell transplantation (HSCT). Designated orphan drug by FDA for treatment of hepatic VOD.

Improves day-100 post-HSCT survival rates compared with historical controls receiving supportive or other therapies.

• Generic Name: toremifene
• Dosage Forms: n.a.
• Other Brand Names: Fareston

Toremifene blocks estrogen from reaching cancer cells. Certain types of breast cancer require estrogen to grow.

Toremifene is used in postmenopausal women to treat metastatic breast cancer (cancer that has spread to other parts of the body).

Toremifene may also be used for purposes not listed in this medication guide.