Defibrotide Sodium and Uramit MB

• Generic Name: defibrotide
• Dosage Forms: n.a.
• Other Brand Names: Defitelio

Treatment of hepatic VOD, also known as sinusoidal obstruction syndrome (SOS), with renal or pulmonary dysfunction following hematopoietic stem cell transplantation (HSCT). Designated orphan drug by FDA for treatment of hepatic VOD.

Improves day-100 post-HSCT survival rates compared with historical controls receiving supportive or other therapies.

• Generic Name: hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate
• Dosage Forms: capsule
• Other Brand Names: Azuphen MB, Hyolev MB, Phosphasal, UR N-C, Uramit MB, Urelle, Uribel, Urimar-T, Urin D/S, Uro-L, Ustell, Utira-C, Uro-MP, Vilamit MB, Vilevev MB, UR N-C, Urelle, Uretron D/S, Urin DS, Uro-458, UroAv-81, UroAv-B, Uticap, Utrona-C

Hyoscyamine produces many effects in the body, including relief from muscle spasms.

Methenamine and methylene blue work as mild antiseptics that fight bacteria in the urine and bladder.

Phenyl salicylate is a mild pain reliever.

Sodium biphosphate is a form of phosphorus, which is a naturally occurring substance that is important in every cell in the body.

Uramit MB is a combination medicine used to treat bladder irritation (pain, spasms, inflammation) caused by urinary tract infection. Uramit MB is also used to prevent bladder discomfort during a medical procedure.

Uramit MB may also be used for purposes not listed in this medication guide.