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Dehydrated Alcohol and Norpace

Determining the interaction of Dehydrated Alcohol and Norpace and the possibility of their joint administration.

Check result:
Dehydrated Alcohol <> Norpace
Relevance: 03.12.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Ethanol significantly increases the renal elimination of disopyramide, apparently by inducing diuresis (inhibition of antidiuretic hormone). Limited data show that ethanol does not, however, significantly affect the elimination half-life or total plasma clearance of disopyramide. No special precautions appear to be necessary.

References
  • Olsen H, Bredesen JE, Lunde PK "Effect of ethanol intake on disopyramide elimination by healthy volunteers." Eur J Clin Pharmacol 25 (1983): 103-5
Dehydrated Alcohol

Generic Name: ethanol

Brand name: Ablysinol

Synonyms: n.a.

Norpace

Generic Name: disopyramide

Brand name: Norpace, Norpace CR

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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