Dehydrated Alcohol Injection and Trimethoprim
Determining the interaction of Dehydrated Alcohol Injection and Trimethoprim and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using trimethoprim together with ethanol. Do not drink alcohol while you are taking trimethoprim. You may have unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Check your food and medicine labels to be sure these products do not contain alcohol. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Two cases have been reported in which patients on sulfamethoxazole-trimethoprim therapy, after consuming beer, reported flushing, heart palpitations, dyspnea, headache, and nausea (disulfiram - alcohol type reactions). The proposed mechanism is inhibition of acetaldehyde dehydrogenase resulting in acetaldehyde accumulation.
MANAGEMENT: Patients should be alerted to the potential for this interaction, and advised to avoid alcohol while taking sulfamethoxazole-trimethoprim.
- Heelon MW, White M "Disulfiram-cotrimoxazole reaction." Pharmacotherapy 18 (1998): 869-70
Generic Name: ethanol
Brand name: Ablysinol
Synonyms: Alcohol
Generic Name: trimethoprim
Brand name: Primsol, Trimpex, Proloprim
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Dehydrated Alcohol Injection-Trimethoprim Oral Solution
- Dehydrated Alcohol Injection-Trimethoprim Tablets
- Dehydrated Alcohol Injection-Trimipramine
- Dehydrated Alcohol Injection-Trimipramine Capsules
- Dehydrated Alcohol Injection-Trimipramine Maleate
- Dehydrated Alcohol Injection-Trimo San Jelly
- Trimethoprim-Dekpak 13 Day Taperpak
- Trimethoprim-Del-Beta
- Trimethoprim-Delacort
- Trimethoprim-Delafloxacin
- Trimethoprim-Delafloxacin Injection
- Trimethoprim-Delafloxacin Intravenous