Delavirdine and Nexium 24HR (Esomeprazole Delayed-Release Capsules)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using delavirdine together with esomeprazole is not recommended. By reducing stomach acid, esomeprazole can decrease the absorption and blood levels of delavirdine and make the medication less effective against HIV. Your doctor or pharmacist may be able to offer suggestions on safer alternatives if you require treatment for stomach acid or ulcer while you are being treated with delavirdine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Theoretically, H2 antagonists and proton pump inhibitors may decrease the gastrointestinal absorption of delavirdine. The proposed mechanism is a pH-dependent reduction in drug dissolution or absorption.

MANAGEMENT: While the clinical significance of this potential interaction is unknown, the manufacturer recommends against the chronic use of these drugs with delavirdine due to the risk of treatment failure and emergence of drug resistance associated with subtherapeutic levels of delavirdine.

Delavirdine

Generic Name: delavirdine

Brand name: Rescriptor

Synonyms: n.a.

What is Delavirdine?

Nexium 24HR (Esomeprazole Delayed-Release Capsules)

Generic Name: esomeprazole

Brand name: NexIUM 24HR, Esomeprazole Strontium, Nexium, Nexium, Nexium IV

Synonyms: NexIUM 24HR (Esomeprazole Delayed-Release Tablets)

What is Nexium 24HR (Esomeprazole Delayed-Release Capsules)?