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Delavirdine and Prozac Weekly

Determining the interaction of Delavirdine and Prozac Weekly and the possibility of their joint administration.

Check result:
Delavirdine <> Prozac Weekly
Relevance: 27.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using delavirdine together with FLUoxetine may increase the effects of delavirdine. Contact your doctor if you experience sore throat, headache, rash, easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms, or any other signs of new infection. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Trough concentrations of delavirdine are increased by as much as 50% when it is used in combination with fluoxetine. The mechanism of the interaction is unknown.

MANAGEMENT: No specific dosing adjustments are suggested, however, close clinical monitoring for signs of delavirdine toxicity (rash, fever, blood and chemistry abnormalities) is recommended.

References
  • "Product Information. Rescriptor (delavirdine)." Pharmacia and Upjohn, Kalamazoo, MI.
Delavirdine

Generic Name: delavirdine

Brand name: Rescriptor

Synonyms: n.a.

Prozac Weekly

Generic Name: fluoxetine

Brand name: Prozac, Prozac Weekly, Sarafem, PROzac Pulvules, Rapiflux, Selfemra

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction