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Delavirdine Mesylate and Didanosine

Determining the interaction of Delavirdine Mesylate and Didanosine and the possibility of their joint administration.

Check result:

Delavirdine Mesylate <> Didanosine

Relevance: 11.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using didanosine together with delavirdine may alter the effects of both medications. Didanosine and delavirdine should be administered at least one hour apart. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Simultaneous administration of delavirdine and didanosine has been reported to decrease the bioavailability of both drugs by approximately 20%, compared to administration at least 1 hour apart. The mechanism of the interaction is unknown.

MANAGEMENT: If these drugs are used together they should be administered at least one hour apart.

References

"Product Information. Rescriptor (delavirdine)." Pharmacia and Upjohn, Kalamazoo, MI.

Delavirdine Mesylate

Generic Name: delavirdine

Brand name: Rescriptor

Synonyms: Delavirdine

What is Delavirdine Mesylate?

Didanosine

Generic Name: didanosine

Brand name: Videx, Videx EC

Synonyms: n.a.

What is Didanosine?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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