Demadex and Eculizumab Intravenous

• Generic Name: torsemide
• Dosage Forms: tablet
• Other Brand Names: Demadex, Demadex IV.

Demadex is a loop diuretic (water pill) that prevents your body from absorbing too much salt, allowing the salt to instead be passed in your urine.

Demadex treats fluid retention (edema) in people with congestive heart failure, liver disease, kidney disease, or kidney failure. This medication is also used to treat high blood pressure (hypertension).

Demadex may also be used for purposes not listed in this medication guide.

• Generic Name: eculizumab
• Dosage Forms: n.a.
• Other Brand Names: Soliris

Eculizumab injection is used to treat a type of blood disease called paroxysmal nocturnal hemoglobinuria (PNH). Eculizumab helps reduce red blood cell destruction or breakdown (hemolysis) in patients with PNH.

Eculizumab is also used to treat a serious kidney disorder called atypical hemolytic uremic syndrome (aHUS).

Eculizumab injection is also used to treat a nerve and muscle disease called generalized myasthenia gravis (gMG) in patients who are anti-acetylcholine receptor (AchR) antibody positive.

Eculizumab injection is a monoclonal antibody that works on the immune system.

Eculizumab is available only under a restricted distribution program called Soliris® REMS (Risk Evaluation and Mitigation Strategy) Program.