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Demulen 1/50 and Letrozole

Determining the interaction of Demulen 1/50 and Letrozole and the possibility of their joint administration.

Check result:

Demulen 1/50 <> Letrozole

Relevance: 03.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using ethinyl estradiol together with letrozole. Using these medications together can make letrozole less effective. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Theoretically, estrogen-containing drugs may negate the pharmacologic effects of aromatase inhibitors in the treatment of hormone-dependent breast cancer. Aromatase inhibitors induce a state of estrogen deprivation in postmenopausal women by inhibiting the conversion of androgens to estrogens in adrenal and ovarian tissues, thus estrogen administration would be expected to reverse their therapeutic effects.

MANAGEMENT: Use of estrogen-containing products should be avoided during aromatase inhibitor therapy.

References

"Product Information. Aromasin (exemestane)" Pharmacia & Upjohn, Kalamazoo, MI.
"Product Information. Femara (letrozole)." Novartis Pharmaceuticals, East Hanover, NJ.
"Product Information. Arimidex (anastrozole)." Zeneca Pharmaceuticals, Wilmington, DE.

Demulen 1/50

Generic Name: ethinyl estradiol / ethynodiol

Brand name: Kelnor, Zovia 1/35, Zovia 1/50, Demulen 1/35, Demulen 1/50, Zovia 1/35e, Kelnor 1/50, Kelnor 1/35, Zovia 1/50e

Synonyms: Demulen 1/50 (Oral)

What is Demulen 1/50?

Letrozole

Generic Name: letrozole

Brand name: Femara

Synonyms: n.a.

What is Letrozole?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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