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Demulen 1/50 and Linzess

Determining the interaction of Demulen 1/50 and Linzess and the possibility of their joint administration.

Check result:

Demulen 1/50 <> Linzess

Relevance: 03.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Linaclotide may cause diarrhea, which may affect the absorption of any other oral medication you may take. If you develop diarrhea and are taking ethinyl estradiol for birth control, you may need an additional method of contraception as a backup. Talk to your healthcare provider if you have questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADDITIONAL CONTRACEPTION RECOMMENDED: The absorption and efficacy of oral contraceptives may be reduced if severe diarrhea occurs with linaclotide treatment. Linaclotide has been associated with severe and prolonged diarrhea.

MANAGEMENT: In patients who develop severe diarrhea during treatment with linaclotide, European labeling recommends use of an additional contraceptive method to prevent possible failure of oral contraception.

References

EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports. Available from: URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid."
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
"Product Information. Linzess (linaclotide)." Forest Pharmaceuticals, St. Louis, MO.

Demulen 1/50

Generic Name: ethinyl estradiol / ethynodiol

Brand name: Kelnor, Zovia 1/35, Zovia 1/50, Demulen 1/35, Demulen 1/50, Zovia 1/35e, Kelnor 1/50, Kelnor 1/35, Zovia 1/50e

Synonyms: Demulen 1/50 (Oral)

What is Demulen 1/50?

Linzess

Generic Name: linaclotide

Brand name: Linzess

Synonyms: n.a.

What is Linzess?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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