Denileukin Diftitox and Precedex

• Generic Name: denileukin diftitox
• Dosage Forms: n.a.
• Other Brand Names: Ontak

Treatment of persistent or recurrent cutaneous T-cell lymphoma (CTCL) in patients whose malignant cells express the CD25 component of the IL-2 receptor (designated an orphan drug by FDA for this use).

Safety and efficacy in patients with CTCL whose malignant cells do not express the CD25 component of the IL-2 receptor not established but currently being studied.

• Generic Name: dexmedetomidine
• Dosage Forms: injection, solution
• Other Brand Names: Precedex

Precedex is a sedative that is used to sedate a patient who is under intensive medical care and needs a mechanical ventilator (breathing machine).

Before a ventilator is used, a breathing tube must be inserted through the mouth and into the patient's airway, a procedure called intubation. The tube is then attached to the ventilator, which pumps air slowly into the lungs to control the patient's breathing. Sedation with Precedex can help keep the patient relaxed and comfortable while the ventilator and tube are in place.

Precedex is also used during anesthesia to get a patient ready for a surgery or other medical procedure.

Precedex may also be used for purposes not listed in this medication guide.