DentiPatch and Doxorubicin Intravenous
Determining the interaction of DentiPatch and Doxorubicin Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited in vitro data have shown that the two local anesthetics, procaine and lidocaine, can act synergistically with doxorubicin to inhibit cell growth. Data suggest that clinically achievable concentrations of these drugs could enhance doxorubicin cytotoxicity. The clinical relevance of these data is unknown.
- Chlebowski RT, Block JB, Cundiff D, Dietrich MF "Doxorubicin cytotoxicity enhanced by local anesthetics in a human melanoma cell line." Cancer Treat Rep 66 (1982): 121-125
Generic Name: lidocaine
Brand name: UAD Caine, Xylocaine HCl, Xylocaine-MPF, Lidoject 1, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, Anestacaine
Synonyms: n.a.
Generic Name: doxorubicin
Brand name: Adriamycin, Adriamycin RDF, Rubex, Adriamycin PFS
Synonyms: Doxorubicin, DOXOrubicin (Conventional)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- DentiPatch-Doxorubicin liposomal
- DentiPatch-Doxorubicin liposome Intravenous
- DentiPatch-Doxy 100
- DentiPatch-Doxycycline
- DentiPatch-Doxycycline Calcium
- DentiPatch-Doxycycline Capsules (Rosacea)
- Doxorubicin Intravenous-Deoxycholic acid
- Doxorubicin Intravenous-Deoxycholic acid Subcutaneous
- Doxorubicin Intravenous-Depacon
- Doxorubicin Intravenous-Depade
- Doxorubicin Intravenous-Depakene
- Doxorubicin Intravenous-Depakene (Valproic Acid Capsules)