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Depakene and Temodar

Determining the interaction of Depakene and Temodar and the possibility of their joint administration.

Check result:

Depakene <> Temodar

Relevance: 20.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Administration of temozolomide with valproic acid decreases the clearance of temozolomide by about 5%. The clinical implication of this effect is unknown. The patient should be observed for increased adverse effects if these drugs are given concomitantly.

References

"Product Information. Temodar (temozolomide)" Schering Corporation, Kenilworth, NJ.

Depakene

Generic Name: valproic acid

Brand name: Depakene, Depacon, Stavzor, Valproate Sodium

Synonyms: n.a.

What is Depakene?

Temodar

Generic Name: temozolomide

Brand name: Temodar

Synonyms: n.a.

What is Temodar?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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