Depakote and Sitagliptin and simvastatin

• Generic Name: divalproex sodium
• Dosage Forms: tablet, delayed release
• Other Brand Names: Depakene, Depacon, Depakote ER, Depakote Sprinkles, Depakote

Depakote (divalproex sodium) affects chemicals in the body that may be involved in causing seizures.

Depakote is used to treat various types of seizure disorders. This medicine is sometimes used together with other seizure medications.

Depakote is also used to treat manic episodes related to bipolar disorder (manic depression), and to prevent migraine headaches.

Depakote may also be used for purposes not listed in this medication guide.

• Generic Name: simvastatin / sitagliptin
• Dosage Forms: n.a.
• Other Brand Names: Juvisync

Sitagliptin and simvastatin combination is used together with a proper diet and exercise to treat type 2 diabetes. It is also used together with a proper diet to treat high cholesterol and triglyceride (fats) levels in the blood. Sitagliptin and simvastatin may help prevent medical problems caused by clogged blood vessels such as heart attacks and strokes.

Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It helps to control blood sugar levels by increasing substances in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.

Simvastatin belongs to the group of medicines called statins. It works to reduce the amount of cholesterol in the blood by blocking the production of cholesterol.

Sitagliptin and simvastatin was available only with your doctor's prescription. The Juvisync™ product will no longer be marketed in the United States as of September 26, 2013, but may be available in other countries.