Depakote ER and Matzim LA

• Generic Name: divalproex sodium
• Dosage Forms: tablet, extended release
• Other Brand Names: Depakote ER, Depakote Sprinkles, Depakene, Depacon, Depakote

Depakote ER affects chemicals in the body that may be involved in causing seizures.

Depakote ER is used to treat various types of seizure disorders. This medicine is sometimes used together with other seizure medications.

Depakote ER is also used to treat manic episodes related to bipolar disorder (manic depression), and to prevent migraine headaches.

Depakote ER may also be used for purposes not listed in this medication guide.

• Generic Name: diltiazem
• Dosage Forms: tablet, extended release
• Other Brand Names: Cardizem, Cartia XT, Dilacor XR, Dilt-CD, Diltia XT, Diltzac, Matzim LA, Taztia XT, Tiazac, Cardizem CD, Dilt-XR, Tiazac, Cardizem LA, Tiazac Extended Release Capsules

Diltiazem is used alone or together with other medicines to treat angina (severe chest pain) or hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Diltiazem is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, diltiazem relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.