Deplin and Diacomit

• Generic Name: l-methylfolate
• Dosage Forms: n.a.
• Other Brand Names: Deplin, L-Methylfolate Formula, XaQuil XR, L-Methylfolate Formula 75

Folate is a form of B vitamin that occurs naturally in many foods. Folic acid is the man-made form of folate that is added to processed foods or vitamin and mineral supplements. Folate is needed in the human body for production of red blood cells.

A lack (deficiency) of folate in the human body can be caused by certain diseases, by taking certain medications, or by not getting enough folate in your diet. Folate deficiency can lead to decreased red blood cells, or anemia. Folate deficiency can also cause high levels of a certain amino acid in the blood, a condition called hyperhomocysteinemia (HYE-per-HOE-moe-sis-tin-EE-mee-a).

Deplin is a medical food for use in people who have conditions related to folate deficiency. This medicine is also used in people with major depressive disorder who have folate deficiency, or in people with schizophrenia who have hyperhomocysteinemia related to folate deficiency.

Deplin is not an antidepressant or anti-psychotic medication. However, this medicine may enhance the effects of antidepressant medications.

Deplin may also be used for purposes not listed in this medication guide.

• Generic Name: stiripentol
• Dosage Forms: capsule
• Other Brand Names: Diacomit

Diacomit (stiripentol) is a prescription medicine used to treat seizures associated with Dravet syndrome. Dravet syndrome is a rare chronic form of epilepsy that begins in the first year of life and causes frequent or prolonged seizures.

Diacomit is used along with clobazam for use in adults and children at least 2 years old.

It is not known if Diacomit is safe and effective in children under 2 years of age.

There is no clinical data to support the use of Diacomit alone to treat Dravet syndrome.