Deplin and Norgesic

• Generic Name: l-methylfolate
• Dosage Forms: n.a.
• Other Brand Names: Deplin, L-Methylfolate Formula, XaQuil XR, L-Methylfolate Formula 75

Folate is a form of B vitamin that occurs naturally in many foods. Folic acid is the man-made form of folate that is added to processed foods or vitamin and mineral supplements. Folate is needed in the human body for production of red blood cells.

A lack (deficiency) of folate in the human body can be caused by certain diseases, by taking certain medications, or by not getting enough folate in your diet. Folate deficiency can lead to decreased red blood cells, or anemia. Folate deficiency can also cause high levels of a certain amino acid in the blood, a condition called hyperhomocysteinemia (HYE-per-HOE-moe-sis-tin-EE-mee-a).

Deplin is a medical food for use in people who have conditions related to folate deficiency. This medicine is also used in people with major depressive disorder who have folate deficiency, or in people with schizophrenia who have hyperhomocysteinemia related to folate deficiency.

Deplin is not an antidepressant or anti-psychotic medication. However, this medicine may enhance the effects of antidepressant medications.

Deplin may also be used for purposes not listed in this medication guide.

• Generic Name: aspirin / caffeine / orphenadrine
• Dosage Forms: tablet, multilayer
• Other Brand Names: Norgesic, Norgesic Forte, Orphengesic Forte, Orphengesic

Aspirin is in a class of drugs called salicylates. Aspirin works reducing substances in the body that cause pain and inflammation. It is used to reduce pain, inflammation, and fever.

Caffeine is used in this combination to increase the pain relieving effects of aspirin and orphenadrine.

Orphenadrine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to the brain.

Norgesic (aspirin/caffeine/orphenadrine) is used, along with rest and physical therapy, to treat injuries and other painful muscular conditions.

This medicine may also be used for purposes other than those listed in this medication guide.