Deprizine FusePaq and Lortab (Hydrocodone and Acetaminophen Tablets and Capsules)
Determining the interaction of Deprizine FusePaq and Lortab (Hydrocodone and Acetaminophen Tablets and Capsules) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that ranitidine may potentiate the hepatotoxicity of acetaminophen, however, a double-blind placebo-controlled crossover study has failed to confirm this finding in humans. Acetaminophen dosage adjustments are not indicated.
- Rogers SA, Gale KC, Newton JF, et al "Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity." J Pharmacol Exp Ther 245 (1988): 887-94
- Jack D, Thomas M, Skidmore IF "Ranitidine and paracetamol metabolism." Lancet 2 (1985): 1067
Generic Name: ranitidine
Brand name: Zantac
Synonyms: Ranitidine
Generic Name: acetaminophen / hydrocodone
Brand name: Hycet, Lorcet, Lortab 10/325, Lortab 5/325, Lortab 75/325, Lortab Elixir, Norco, Verdrocet, Vicodin, Xodol, Zamicet, Anexsia, Dolorex Forte, Liquicet, Lortab, Maxidone, Polygesic, Stagesic, Zydone, Zyfrel
Synonyms: Lortab
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Deprizine FusePaq-Lortab Oral Solution
- Deprizine FusePaq-Lortab Tablets
- Deprizine FusePaq-Lortuss DM
- Deprizine FusePaq-Lortuss EX
- Deprizine FusePaq-Lortuss LQ
- Deprizine FusePaq-Loryna
- Lortab (Hydrocodone and Acetaminophen Tablets and Capsules)-Derma Gran AF Topical
- Lortab (Hydrocodone and Acetaminophen Tablets and Capsules)-Derma Numb Spray
- Lortab (Hydrocodone and Acetaminophen Tablets and Capsules)-Derma-Smoothe/FS
- Lortab (Hydrocodone and Acetaminophen Tablets and Capsules)-Derma-Smoothe/FS (Body Oil)
- Lortab (Hydrocodone and Acetaminophen Tablets and Capsules)-Derma-Smoothe/FS (Scalp)
- Lortab (Hydrocodone and Acetaminophen Tablets and Capsules)-Derma-Smoothe/FS Body Oil (Fluocinolone Oil (Body Oil))