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Desflurane and Subsys

Determining the interaction of Desflurane and Subsys and the possibility of their joint administration.

Check result:
Desflurane <> Subsys
Relevance: 25.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Before receiving anesthesia, let your doctor know if you are currently using fentaNYL. Narcotic pain medications like fentaNYL may alter the effects of desflurane, which may reduce the dosage of desflurane required for anesthesia. You should be closely monitored by the surgical staff while you are under anesthesia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Opioids may be expected to decrease the minimum alveolar concentration required for inhalation anesthetics. When these agents are used concomitantly, less inhalation anesthetic may be required.

MANAGEMENT: In general, anesthesia should be titrated to clinical effect by those experienced in anesthesia technique and in the care of patients receiving opioids.

References
  • "Product Information. Ultane (sevoflurane)." Abbott Pharmaceutical, Abbott Park, IL.
  • Inagaki Y, Kuzukawa A "Effects of epidural and intravenous buprenorphine on halothane minimum alveolar anesthetic concentration and hemodynamic responses." Anesth Analg 84 (1997): 100-5
Desflurane

Generic Name: desflurane

Brand name: Suprane

Synonyms: Desflurane Liquid

Subsys

Generic Name: fentanyl

Brand name: Abstral, Fentora, Subsys, Actiq, Duragesic, Ionsys, Lazanda, Onsolis, Sublimaze

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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Disease interaction