Desipramine Hydrochloride and Hydrochlorothiazide and methyldopa
Determining the interaction of Desipramine Hydrochloride and Hydrochlorothiazide and methyldopa and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Isolated reports have suggested that tricyclic antidepressants may decrease the antihypertensive effect of methyldopa. These reports have not been confirmed by other small studies.
- White AG "Methyldopa and amitriptyline." Lancet 2 (1965): 441
- Reid JL, Porsius AJ, Zamboulis C, Polak G, Hamilton CA, Dean CR "The effects of desmethylimipramine on the pharmacological actions of alpha methyldopa in man." Eur J Clin Pharmacol 16 (1979): 75-80
Generic Name: desipramine
Brand name: Norpramin
Synonyms: Desipramine
Generic Name: hydrochlorothiazide / methyldopa
Brand name: Aldoril 15, Aldoril 25, Aldoril D30, Aldoril D50
Synonyms: Methyldopa and Hydrochlorothiazide
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Desipramine Hydrochloride-Hydrochlorothiazide and metoprolol
- Desipramine Hydrochloride-Hydrochlorothiazide and moexipril
- Desipramine Hydrochloride-Hydrochlorothiazide and olmesartan
- Desipramine Hydrochloride-Hydrochlorothiazide and propranolol
- Desipramine Hydrochloride-Hydrochlorothiazide and quinapril
- Desipramine Hydrochloride-Hydrochlorothiazide and spironolactone
- Hydrochlorothiazide and methyldopa-Desirudin
- Hydrochlorothiazide and methyldopa-Desirudin Subcutaneous
- Hydrochlorothiazide and methyldopa-Desloratadine
- Hydrochlorothiazide and methyldopa-Desloratadine and pseudoephedrine
- Hydrochlorothiazide and methyldopa-Desloratadine Oral Solution
- Hydrochlorothiazide and methyldopa-Desloratadine Orally Disintegrating Tablets