Desloratadine and PCE Dispertab
Determining the interaction of Desloratadine and PCE Dispertab and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Erythromycin and ketoconazole may increase the plasma concentrations of desloratadine and its metabolite. The probable mechanism is inhibition of CYP450 hepatic metabolism, although the isoenzymes responsible for desloratadine metabolism have not been identified. There were no clinically significant adverse effects associated with this interaction. Clinical monitoring of patient response and tolerance is recommended when erythromycin or ketoconazole are administered with desloratadine.
- "Product Information. Clarinex (desloratadine)." Schering Corporation, Kenilworth, NJ.
Generic Name: desloratadine
Brand name: Clarinex, Clarinex Reditabs, Neoclarityn, Aerius
Synonyms: n.a.
Generic Name: erythromycin
Brand name: EES. Granules, EES-400 Filmtab, EryPed 200, EryPed 400, Ery-Tab, Erythrocin Lactobionate, Erythrocin Stearate Filmtab, PCE Dispertab, E. E. S, EryPed, Erythrocin, Erythromycin Filmtabs, Erythromycin Lactobionate - IV
Synonyms: PCE Dispertab (Oral), PCE, PCE (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Desloratadine-PCM-LA
- Desloratadine-Pedia Care Multi-Symptom Cold
- Desloratadine-Pedia Poly-Vite Drops with Iron
- Desloratadine-Pedia Relief Cough-Cold
- Desloratadine-Pedia Tri-Vite Drops
- Desloratadine-Pedia-Lax
- PCE Dispertab-Desloratadine and pseudoephedrine
- PCE Dispertab-Desloratadine Oral Solution
- PCE Dispertab-Desloratadine Orally Disintegrating Tablets
- PCE Dispertab-Desloratadine Syrup
- PCE Dispertab-Desloratadine Tablets
- PCE Dispertab-Desmopressin