Dexamethasone Eye Implant and Insert and Eliglustat Tartrate

• Generic Name: dexamethasone ophthalmic
• Dosage Forms: n.a.
• Other Brand Names:

  Dextenza, Dexycu, Ozurdex, Maxidex

• It is used to treat eye swelling.
• It is used to treat eye irritation.

• Generic Name: eliglustat
• Dosage Forms: n.a.
• Other Brand Names: Cerdelga

Long-term treatment of nonneuronopathic (type 1) Gaucher disease in patients who are extensive, intermediate, or poor metabolizers of CYP2D6.

Patient selection and dosing based on CYP2D6 metabolizer status; determine patient's CYP2D6 genotype with an FDA-cleared test prior to initiating therapy.

Ultrarapid CYP2D6 metabolizers may not achieve adequate plasma concentrations to achieve a therapeutic effect. A specific dosage cannot be recommended for patients whose CYP2D6 genotype cannot be determined (indeterminate metabolizers).

Designated an orphan drug by FDA for treatment of type 1 Gaucher disease.