Dexamethasone Injection Solution and Fycompa (Perampanel Tablets)
Determining the interaction of Dexamethasone Injection Solution and Fycompa (Perampanel Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using perampanel together with dexamethasone. Combining these medications may reduce the blood levels and effects of perampanel. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Coadministration with inducers of CYP450 3A4 may decrease the plasma concentrations and pharmacologic effects of perampanel, which is primarily metabolized by the isoenzyme. The interaction has been reported with known CYP450 3A4 inducers such as carbamazepine, oxcarbazepine, and phenytoin.
MANAGEMENT: According to the manufacturer, concomitant use of perampanel with strong CYP450 3A4 inducers should be avoided.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Fycompa (perampanel)." Eisai Inc, Teaneck, NJ.
Generic Name: dexamethasone
Brand name: Baycadron, Decadron, Dexamethasone Intensol, DexPak, TaperDex, Zema-Pak, ZoDex, Zonacort, DexPak 10 Day Taperpak, DexPak 13 DayTaperpak, DexPak 6 DayTaperpak, De-Sone LA, Dexacen-4, Dexasone, Dexasone LA, Solurex, Solurex LA
Synonyms: Dexamethasone, Dexamethasone (Systemic)
Generic Name: perampanel
Brand name: Fycompa
Synonyms: Fycompa
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Fycompa (Perampanel Tablets)-Dexamethasone Intensol
- Fycompa (Perampanel Tablets)-Dexamethasone intraocular
- Fycompa (Perampanel Tablets)-Dexamethasone ophthalmic
- Fycompa (Perampanel Tablets)-Dexamethasone Oral Drops
- Fycompa (Perampanel Tablets)-Dexamethasone SodiumPhosphate
- Fycompa (Perampanel Tablets)-Dexamethasone Solution (Drops)