Dexasone LA injection and Memantine and Donepezil
Determining the interaction of Dexasone LA injection and Memantine and Donepezil and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Dexamethasone may reduce the blood levels and effects of donepezil. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with drugs that are inducers of the CYP450 3A4 and/or 2D6 enzymatic pathways may decrease the plasma concentrations of donepezil. The mechanism is accelerated clearance of donepezil due to enhanced CYP450 activities.
MANAGEMENT: While clinical data are lacking, the possibility of a diminished therapeutic response to donepezil should be considered in patients receiving concomitant inducer agents.
- "Product Information. Aricept (donepezil)." Pfizer US Pharmaceuticals, New York, NY.
Generic Name: dexamethasone
Brand name: De-Sone LA, Dexacen-4, Dexasone, Dexasone LA, Solurex, Solurex LA, Baycadron, Dexamethasone Intensol, DexPak 10 Day Taperpak, DexPak 13 DayTaperpak, DexPak 6 DayTaperpak, Decadron, DexPak, TaperDex, Zema-Pak, ZoDex, Zonacort
Synonyms: Dexasone LA (injection)
Generic Name: donepezil / memantine
Brand name: Namzaric, Namzaric Titration Pack
Synonyms: Donepezil and memantine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Dexasone LA injection-Memantine and Donepezil Capsules
- Dexasone LA injection-Memantine ER capsules
- Dexasone LA injection-Memantine ER Tablets
- Dexasone LA injection-Memantine Extended-Release Capsules
- Dexasone LA injection-Memantine Hydrochloride
- Dexasone LA injection-Memantine Oral Solution
- Memantine and Donepezil-Dexbrompheniramine
- Memantine and Donepezil-Dexbrompheniramine and Acetaminophen Caplets
- Memantine and Donepezil-Dexbrompheniramine and phenylephrine
- Memantine and Donepezil-Dexbrompheniramine and Phenylephrine Syrup
- Memantine and Donepezil-Dexbrompheniramine and Phenylephrine Tablets
- Memantine and Donepezil-Dexbrompheniramine and pseudoephedrine