Dexilant SoluTab and Evekeo ODT
Determining the interaction of Dexilant SoluTab and Evekeo ODT and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using amphetamine together with dexlansoprazole. Combining these medications may affect the onset of effects of amphetamine. Contact your doctor if your condition worsens or you experience increased side effects. Your doctor may be able to prescribe alternative treatments that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of proton pump inhibitors with extended release forms of amphetamine may affect the release rate of amphetamine from the capsule. The mechanism is reduction of gastric acidity. When omeprazole 40 mg/day was concomitantly administered with a mixed salts amphetamine 20 mg, the median Tmax decreased by 1.25 hours for d-amphetamine and by 2.5 hours for l-amphetamine. The systemic exposure (AUC) and maximum plasma concentration (Cmax) were unchanged.
MANAGEMENT: Patients should be monitored for changes in clinical effects during concomitant use.
- "Product Information. Adderall XR (amphetamine-dextroamphetamine)." Shire Richwood Pharmaceutical Company Inc, Florence, KY.
Generic Name: dexlansoprazole
Brand name: Dexilant, Kapidex
Synonyms: Dexilant SoluTab (Oral)
Generic Name: amphetamine
Brand name: Adzenys ER, Adzenys XR-ODT, Dyanavel XR, Evekeo, Evekeo ODT
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Dexilant SoluTab-Evening Primrose
- Dexilant SoluTab-Evening Primrose Oil
- Dexilant SoluTab-Evenity
- Dexilant SoluTab-Evenity Injection
- Dexilant SoluTab-Everolimus
- Dexilant SoluTab-Everolimus Tablets (Afinitor)
- Evekeo ODT-Dexlansoprazole
- Evekeo ODT-Dexlansoprazole Capsules
- Evekeo ODT-Dexmedetomidine
- Evekeo ODT-Dexmedetomidine Hydrochloride
- Evekeo ODT-Dexmedetomidine Hydrochloride Injection
- Evekeo ODT-Dexmedetomidine hydrochloride Injection, Concentrate