Dexmedetomidine hydrochloride Injection, Concentrate and Doxercalciferol

• Generic Name: dexmedetomidine
• Dosage Forms: injection, solution, concentrate
• Other Brand Names: Precedex

Dexmedetomidine is a sedative that is used to sedate a patient who is under intensive medical care and needs a mechanical ventilator (breathing machine).

Before a ventilator is used, a breathing tube must be inserted through the mouth and into the patient's airway, a procedure called intubation. The tube is then attached to the ventilator, which pumps air slowly into the lungs to control the patient's breathing. Sedation with dexmedetomidine can help keep the patient relaxed and comfortable while the ventilator and tube are in place.

Dexmedetomidine is also used during anesthesia to get a patient ready for a surgery or other medical procedure.

Dexmedetomidine may also be used for purposes not listed in this medication guide.

• Generic Name: doxercalciferol
• Dosage Forms: n.a.
• Other Brand Names: Hectorol

Treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD) undergoing dialysis.

Oral doxercalciferol also used in the treatment of secondary hyperparathyroidism in patients with stage 3 or 4 CKD who do not yet require maintenance dialysis (predialysis patients).

Suppresses elevated serum or plasma parathyroid hormone (PTH) concentrations associated with secondary hyperparathyroidism in patients with CKD. Deficient production of biologically active vitamin D metabolites leads to secondary hyperparathyroidism, which contributes to the development of metabolic bone disease.