Dexmedetomidine hydrochloride Injection, Concentrate and Xeljanz

• Generic Name: dexmedetomidine
• Dosage Forms: injection, solution, concentrate
• Other Brand Names: Precedex

Dexmedetomidine is a sedative that is used to sedate a patient who is under intensive medical care and needs a mechanical ventilator (breathing machine).

Before a ventilator is used, a breathing tube must be inserted through the mouth and into the patient's airway, a procedure called intubation. The tube is then attached to the ventilator, which pumps air slowly into the lungs to control the patient's breathing. Sedation with dexmedetomidine can help keep the patient relaxed and comfortable while the ventilator and tube are in place.

Dexmedetomidine is also used during anesthesia to get a patient ready for a surgery or other medical procedure.

Dexmedetomidine may also be used for purposes not listed in this medication guide.

• Generic Name: tofacitinib
• Dosage Forms: tablet, film coated
• Other Brand Names: Xeljanz, Xeljanz XR

Xeljanz (tofacitinib) blocks the activity of certain enzymes in the body that affect immune system function.

Xeljanz is used to treat moderate to severe rheumatoid arthritis or active psoriatic arthritis in adults who have tried methotrexate or other medications without successful treatment of symptoms. Tofacitinib is sometimes given in combination with methotrexate or other arthritis medicines.

Xeljanz is also used to treat adults with moderate to severe ulcerative colitis in adults who cannot use certain other medications, or after other treatments have failed.