Dexrazoxane Hydrochloride and Magonate (Magnesium Gluconate)

• Generic Name: dexrazoxane
• Dosage Forms: n.a.
• Other Brand Names: Totect, Zinecard

Reduction of the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose of ≥300 mg/m2 and would benefit from continued doxorubicin therapy (designated an orphan drug by FDA for this use).

Not recommended for use with initiation of doxorubicin therapy. (See Effectiveness of Cytotoxic Regimens under Cautions.)

• Generic Name: magnesium gluconate
• Dosage Forms: n.a.
• Other Brand Names: Mag-G, Magonate, Magonate Natal, Magtrate, Optimum Magnesium Gluconate

• It is used to treat or prevent low magnesium levels.