Dexrazoxane Hydrochloride and Procort Cream

• Generic Name: dexrazoxane
• Dosage Forms: n.a.
• Other Brand Names: Totect, Zinecard

Reduction of the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose of ≥300 mg/m2 and would benefit from continued doxorubicin therapy (designated an orphan drug by FDA for this use).

Not recommended for use with initiation of doxorubicin therapy. (See Effectiveness of Cytotoxic Regimens under Cautions.)

• Generic Name: hydrocortisone / pramoxine topical
• Dosage Forms: cream
• Other Brand Names:

  Analpram-HC, Epifoam, PramCort, Pramosone, Pramosone E, ProCort, Proctofoam HC, Zone-A, Enzone, Proctocream HC, Zone-A Forte, Rectocort HC, Novacort, Hydropram, HC Pramoxine, Analpram E, ZyPram, Z-Pram, Analpram HC, PramCort, Pramasone

Hydrocortisone is a steroid. It reduces the actions of chemicals in the body that cause inflammation.

Pramoxine is an anesthetic, or "numbing medicine." It works by interfering with pain signals sent from the nerves to the brain.

Hydrocortisone and pramoxine topical (for the skin) is a combination medicine used to treat itching and discomfort caused by allergic reactions, eczema, minor burns, insect bites, or other skin conditions.

Hydrocortisone and pramoxine rectal (for the rectum) is used to treat itching or swelling caused by hemorrhoids or other inflammatory conditions of the rectum or anus.

Hydrocortisone and pramoxine topical may also be used for other purposes not listed in this medication guide.