Dexrazoxane Hydrochloride and Thalidomide

• Generic Name: dexrazoxane
• Dosage Forms: n.a.
• Other Brand Names: Totect, Zinecard

Reduction of the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose of ≥300 mg/m2 and would benefit from continued doxorubicin therapy (designated an orphan drug by FDA for this use).

Not recommended for use with initiation of doxorubicin therapy. (See Effectiveness of Cytotoxic Regimens under Cautions.)

• Generic Name: thalidomide
• Dosage Forms: n.a.
• Other Brand Names: Thalomid

Thalidomide is used together with dexamethasone to treat multiple myeloma (bone marrow cancer). Thalidomide is also used to treat and prevent moderate to severe skin lesions caused by leprosy.

Thalidomide is available only in a 28-day supply from a certified pharmacy under a special program. You must be registered in the program and agree to use birth control as required.

Thalidomide may also be used for purposes not listed in this medication guide.