Dextran 75 and Evenity Injection

• Generic Name: dextran, high molecular weight
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names:

  Dextran 70 6% in 5% Dextrose, Hyskon, Macrodex, Gentran 70, Dextran-HM, Dextran 70 6% in 09% Sodium Chloride

High-molecular weight dextran is a plasma volume expander made from natural sources of sugar (glucose). It works by restoring blood plasma lost through severe bleeding. Severe blood loss can decrease oxygen levels and can lead to organ failure, brain damage, coma, and possibly death. Plasma is needed to circulate red blood cells that deliver oxygen throughout the body.

Dextran is used to treat hypovolemia (decreased volume of circulating blood plasma), that can result from surgery, trauma or injury, severe burns, or other causes of bleeding.

Dextran may also be used for purposes not listed in this medication guide.

• Generic Name: romosozumab
• Dosage Forms: injection, solution
• Other Brand Names: Evenity

Evenity (romosozumab) is a sclerostin inhibitor. Sclerostin suppresses bone formation.

Evenity is a prescription medicine used to treat osteoporosis in postmenopausal women with a high risk of bone fracture who cannot use other osteoporosis medications (or when other medications did not work).

It is not known if Evenity is safe and effective in children. .