Dextran 75 and Gel-One injection

• Generic Name: dextran, high molecular weight
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names:

  Dextran 70 6% in 5% Dextrose, Hyskon, Macrodex, Gentran 70, Dextran-HM, Dextran 70 6% in 09% Sodium Chloride

High-molecular weight dextran is a plasma volume expander made from natural sources of sugar (glucose). It works by restoring blood plasma lost through severe bleeding. Severe blood loss can decrease oxygen levels and can lead to organ failure, brain damage, coma, and possibly death. Plasma is needed to circulate red blood cells that deliver oxygen throughout the body.

Dextran is used to treat hypovolemia (decreased volume of circulating blood plasma), that can result from surgery, trauma or injury, severe burns, or other causes of bleeding.

Dextran may also be used for purposes not listed in this medication guide.

• Generic Name: sodium hyaluronate
• Dosage Forms: n.a.
• Other Brand Names: Durolane, Euflexxa, Gel-One, Gelsyn-3, Hyalgan, Supartz, Supartz FX, Visco-3, Trivisc, GenVisc 850, Monovisc, Orthovisc, Synvisc, Synvisc-One

Gel-One is similar to the fluid that surrounds the joints in your body. This fluid acts as a lubricant and shock absorber for the joints.

Gel-One is used to treat knee pain caused by osteoarthritis.

Gel-One is usually given when other arthritis medications have not been effective.

Gel-One may also be used for purposes not listed in this medication guide.