Dextran 75 and Nexium I.V. Injection

• Generic Name: dextran, high molecular weight
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names:

  Dextran 70 6% in 5% Dextrose, Hyskon, Macrodex, Gentran 70, Dextran-HM, Dextran 70 6% in 09% Sodium Chloride

High-molecular weight dextran is a plasma volume expander made from natural sources of sugar (glucose). It works by restoring blood plasma lost through severe bleeding. Severe blood loss can decrease oxygen levels and can lead to organ failure, brain damage, coma, and possibly death. Plasma is needed to circulate red blood cells that deliver oxygen throughout the body.

Dextran is used to treat hypovolemia (decreased volume of circulating blood plasma), that can result from surgery, trauma or injury, severe burns, or other causes of bleeding.

Dextran may also be used for purposes not listed in this medication guide.

• Generic Name: esomeprazole
• Dosage Forms: n.a.
• Other Brand Names: Esomeprazole Strontium, Nexium, Nexium, NexIUM 24HR, Nexium IV

Nexium injection (esomeprazole sodium) is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

Nexium injection is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Nexium I.V. is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Nexium injection is also used to lower the risk of a stomach ulcer bleeding again after an endoscopy treatment.