Dextran 75 and Tocilizumab Auto-Injectors

• Generic Name: dextran, high molecular weight
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names:

  Dextran 70 6% in 5% Dextrose, Hyskon, Macrodex, Gentran 70, Dextran-HM, Dextran 70 6% in 09% Sodium Chloride

High-molecular weight dextran is a plasma volume expander made from natural sources of sugar (glucose). It works by restoring blood plasma lost through severe bleeding. Severe blood loss can decrease oxygen levels and can lead to organ failure, brain damage, coma, and possibly death. Plasma is needed to circulate red blood cells that deliver oxygen throughout the body.

Dextran is used to treat hypovolemia (decreased volume of circulating blood plasma), that can result from surgery, trauma or injury, severe burns, or other causes of bleeding.

Dextran may also be used for purposes not listed in this medication guide.

• Generic Name: tocilizumab
• Dosage Forms: n.a.
• Other Brand Names: Actemra, Actemra ACTPen

• It is used to treat some types of arthritis.
• It is used to treat a certain artery problem called giant cell arteritis (GCA).
• It is used to treat cytokine release syndrome (CRS).
• It may be given to you for other reasons. Talk with the doctor.