Dextromethorphan Hydrobromide and Sirturo

• Generic Name: dextromethorphan
• Dosage Forms: n.a.
• Other Brand Names: Babee Cof, Benylin DM Pediatric, Buckleys Mixture, Creomulsion, Creo-Terpin, DayQuil Cough, Delsym, Delsym 12 Hour Cough Relief, Elixsure Cough, Robafen Cough Liquidgels, Robitussin CoughGels, Scot-Tussin Diabetic, Silphen DM, St. Joseph Cough Suppressant, Sucrets DM Cough, Theraflu Thin Strips Cough, Triaminic Long Acting Cough, DexAlone, Hold, Sucrets 4-Hour Cough Drops, Robitussin Maximum Strength, Vicks Formula 44

Temporary relief of coughs (antitussive, cough suppressant) caused by minor throat and bronchial irritation that may occur with common colds, allergies, or inhaled irritants.

Used in fixed combination with other agents (e.g., acetaminophen, brompheniramine, chlorpheniramine, doxylamine, guaifenesin, phenylephrine, pseudoephedrine) for the temporary relief of coughs and/or other symptoms (e.g., rhinorrhea, sneezing, lacrimation, itching eyes, oronasopharyngeal itching, nasal congestion) associated with seasonal (e.g., hay fever) or perennial allergic rhinitis, other upper respiratory allergies, or the common cold.

Most effective in the treatment of chronic, nonproductive cough.

In pediatric patients <2 years of age, OTC cough and cold preparations (i.e., containing cough suppressants [including dextromethorphan], antihistamines, expectorants, and/or nasal decongestants) were not more effective than placebo in reducing acute cough and other symptoms of upper respiratory tract infection and reportedly are associated with adverse events and sometimes death (albeit rarely). (See Pediatric Use under Cautions.)

Abuse and recreational use reported. (See Abuse Potential under Cautions.)

• Generic Name: bedaquiline
• Dosage Forms: n.a.
• Other Brand Names: Sirturo

Sirturo (bedaquiline) is an antibiotic that fights bacteria.

Sirturo is used together with other medications to treat tuberculosis of the lungs that has been resistant to other antibacterial medications.

Sirturo is for use in adults and children at least 12 years old and weighing at least 66 pounds (30 kilograms).

Sirturo can cause serious and sometimes fatal side effects. This medicine should be used only if you have no other treatment options.