Dextromethorphan Hydrobromide and Quinidine Sulfate and Diphtheria and tetanus vaccine Intramuscular

• Generic Name: dextromethorphan / quinidine
• Dosage Forms: n.a.
• Other Brand Names: Nuedexta

The fixed combination of dextromethorphan hydrobromide and quinidine sulfate (dextromethorphan/quinidine; Nuedexta) is used in the treatment of PBA.

PBA occurs secondary to various otherwise unrelated neurologic conditions (e.g., amyotrophic lateral sclerosis [ALS], multiple sclerosis [MS], dementia of the Alzheimer's type [Alzheimer's disease] or other dementia, parkinsonian syndrome, stroke, traumatic brain injury) and is characterized by involuntary, sudden, uncontrollable, and frequent episodes of laughing and/or crying. PBA episodes typically occur out of proportion or incongruent to the underlying emotional state.

Studies supporting efficacy in PBA were conducted in patients with underlying ALS or MS.

Safety and efficacy in the treatment of other common types of emotional lability (e.g., those occurring in patients with Alzheimer's disease and other dementias) not established.

• Generic Name: diphtheria toxoid / tetanus toxoid
• Dosage Forms: n.a.
• Other Brand Names:

  Diphtheria-Tetanus Toxoids, Pediatric, Decavac, Tenivac

Diphtheria and tetanus vaccine is a combination vaccine that is given to protect against infections caused by diphtheria and tetanus (lockjaw). The vaccine works by causing the body to produce its own protection (antibodies) against these diseases. This vaccine is given to children 6 weeks of age and older, teenagers, and adults.

Diphtheria is a serious illness that can cause breathing problems, heart problems, nerve damage, pneumonia, and possibly death. The risk for serious illness is greater in very young children and the elderly.

Tetanus (also known as lockjaw) is a very serious illness that causes severe muscle spasms that make the muscles very rigid or stiff. The muscle spasms can be strong enough to cause bone fractures in the spine. The disease can also cause breathing problems, swallowing problems, seizures, and possibly death.

This vaccine is to be administered only by or under the direct supervision of a doctor.